Investigation of the Short-Term Effect of Chemonucleolysis with Chondroitinase ABC.

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Investigation of the short-term effect of chemonucleolysis with chondroitinase ABC.

Chondroitinase ABC (C-ABC) is expected to be a novel agent for chemonucleolysis. The effect of C-ABC was investigated by magnetic resonance (MR) and radiograph. C-ABC was administered into the lumbar intervertebral disks on the clinically normal beagles (n=5), in a dose of 50 microl (12.5 units as C-ABC). MR scans were performed pre-dose, and 1, 3, 7, 14 and 28 days after administration of C-AB...

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ژورنال

عنوان ژورنال: Journal of Veterinary Medical Science

سال: 2001

ISSN: 0916-7250,1347-7439

DOI: 10.1292/jvms.63.521